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MINUTES OF THE NUTRITION COORDINATING COMMITTEE (NCC) …

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MINUTES OF THE NUTRITION COORDINATING COMMITTEE (NCC)
MEETING, NATIONAL INSTITUTES OF HEALTH (NIH)
Rockledge 2, Conference Room 9100-9004, Bethesda MD
September 1, 2005, 2:00-4:00 PM

WELCOME
Dr. Van Hubbard, Director, Division of Nutrition Research Coordination (DNRC)
convened the meeting at 2:00 PM and welcomed participants. Participating via
phone were Dr. Jennifer Seymour, Centers for Disease Control and Prevention
(CDC); Dr. Elizabeth Maull, National Institute of Environmental Health Sciences
(NIEHS); CAPT Tammy Brown, Indian Health Services (IHS); Dr. Deb Olster,
NIH Office of Behavioral and Social Sciences Research (OBSSR); Dr. Judy
Finkelstein, National Institute on Aging (NIA); COL Karl Friedl, Department of
Defense (DoD); COL Gaston Bathalon, DoD; Ms. Martina Vogel-Taylor, NIH
Office of the Director (OD); Dr. Barry Portnoy, NIH OD; Dr. Molly Kretsch,
Agriculture Research Service (ARS) USDA; Dr. Susan Welsh, Cooperative State
Research, Education, and Extension Service (CSREES), USDA; Dr. Natalie
Tomitch, Fogarty International Center (FIC); Dr. Sharon Adamo, and Health
Resources and Services Administration (HRSA). Dr. Hubbard welcomed Dr.
Lawrence Yager as the new NCC representative from the National Center for
Research Resources. The agenda for the meeting is provided as Appendix A,
and the list of attendees is provided as Appendix B.

APPROVAL OF MINUTES FROM THE JULY 7, 2005 NCC MEETING
Minutes from the July 7, 2005, NCC Meeting had previously been sent to NCC
members via email. Dr. Hubbard asked if there were any corrections to the
minutes. There were none. Dr. John Milner, National Cancer Institute (NCI),
made a motion to approve the minutes, and Dr. Sooja Kim, Center for Scientific
Review (CSR), seconded the motion. The minutes were thus approved and will
be posted on the DNRC website, http://www.dnrc.nih.gov, along with the minutes
from previous NCC Meetings.

SCIENTIFIC PRESENTATION
Dr. Jill Reedy, Cancer Prevention Fellow, NCI, provided a presentation on A
Comparison of Three Food Guides: The USDA Food Guide, DASH Eating Plan,
and Willett's Healthy Eating Pyramid. These three food guides are based on
different areas of nutritional science and distinct evaluation strategies. The
USDA Food Guide, MyPyramid, was designed to align with the 2005 Dietary
Guidelines for Americans while translating the nutrient recommendations from
the Institute of Medicine's (IOM) Dietary Reference Intakes (DRIs) into food-
based recommendations; its evaluation was based on nutritional adequacy,
assuming typical food choices within food groups. The DASH (Dietary
Approaches to Stop Hypertension) Eating Plan was derived from the DASH diet-
specific foods and amounts fed to participants in the DASH trial and was based
on evidence that a given dietary pattern could lead to a significant reduction in
hypertension. The study was an eight-week randomized clinical trial, which
found that the DASH diet decreased blood pressure compared to a control diet.
Dr. Walter Willett's Healthy Eating Pyramid was developed through
epidemiological research that showed specific diet-related measures to be
associated with a reduced risk of chronic disease; it was assessed by
constructing a diet quality index based on similar, but not identical, measures and
finding that it predicted chronic disease risk in a given cohort. The presentation
compared the food-based recommendations of the three food guides and the
nutritional adequacy of diets that meet them. To compare the nutritional
adequacy, the USDA composite approach was used which assumes typical
choices within each food group based on population-weighted estimates. There
were similarities among the food guides regarding almost all food group
recommendations for both amount and type of foods. Overall nutritional
adequacy was also similar.

NIH OFFICE OF DIETARY SUPPLEMENTS (ODS)
Dr. Beth Yetley, ODS, provided an update of the activities of that Office.
Upcoming ODS conferences and workshops include:
- September 14, 2005. Workshop on Animal Diets for Evaluating Dietary
Phytoestrogens. Sponsored by ODS and NIEHS. Research Triangle Park NC.
Contact Dr. Yetley, ODS, or Dr. Jerry Heindel, NIEHS.
- October 3, 2005. Conference on the Role of Betaine in the Treatment of
Alcoholic Liver Disease. Sponsored by the National Institute for Alcohol Abuse
and Alcoholism (NIAAA) and ODS. Holiday Inn, Bethesda MD. Registration
information at http://www.blsmeetings.net/2525/. Contact Dr. Vishnu Purohit,
NIAAA, or Dr. Christine Swanson, ODS.
- October 6, 2005. Workshop on Evaluating Alternative Treatments for Children
and Adolescents with Autism. Contact Dr. Paul Coates, ODS. There will be
limited seating capacity for this workshop.
- October 24-25, 2005. Frontiers in Metabolomics for Cancer Research.
Sponsored by NCI and ODS. Rockville MD. Contact Dr. Young Kim, NCI, Dr.
Padma Maruvada, NCI, or Dr. Yetley, ODS.
The AHRQ Evidence-Based Review on Soy, Effects on Health Outcomes
requested by National Center for Complementary and Alternative Medicine
(NCCAM) and ODS has been completed. This was a systematic review to
describe the range of soy products and outcomes that have been studied, to
summarize the effects of soy consumption to prevent a wide variety of medical
conditions in healthy adults, and to summarize adverse events related to soy
consumption. The conclusions of this review are: Soy products appear to exert
a small benefit on LDL and triglycerides; these effects may be of small clinical
effect in individuals, although possibly large enough to have a population-wide
effect. The inconsistent association between soy protein dose and effect, and
the lack of association between soy isoflavone dose and effect, limit possible
determination of an appropriate amount of soy product needed for lipid reduction.
Soy products may reduce menopausal symptoms in post-menopausal women.
The current literature does not support other effects of soy products. However,
other than menopausal- and menstrual-related symptoms, no clinical outcomes

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were evaluated. The evidence from human studies does not suggest any
worrisome adverse events beyond mild gastrointestinal intolerance. Conclusions
were often limited due to small numbers of studies or heterogeneity across
studies. Given the large amount of heterogeneity and inadequate reporting,
particularly related to soy protein and isoflavone dose, many questions remain as
to whether specific soy products in adequate doses may be of benefit in specific
populations. Further, well-conducted studies are needed to clarify the effect of
soy dose on lipid parameters and to determine whether soy components other
than protein or isoflavones may be responsible for the lipid effects seen
(http://www.ahrq.gov/clinic/tp/soytp.htm). [Summary (Publication No. 05-E024-
1); Evidence Report (Publication No. 05-E024-2) (PDF Files Download)].
The AHRQ Evidenced-Based Report on Omega-3 Fatty Acids, Effects on
Child and Maternal Health has been completed with the following summary:
Studies investigating the influence of omega-3 fatty acids on child and maternal
health revealed the absence of a notable safety profile (i.e., moderate-to-severe
adverse events). Pregnancy outcomes were either unaffected by omega-3 fatty
acid supplementation, or the results were inconclusive. Results suggested the
absence of effects with respect to the impact of supplementation on the
incidence of GHT, preeclampsia or eclampsia, as well as on infants being born
SGA. However, regarding evaluations of the duration of gestation, some
discrepancies were observed, although most of the studies failed to detect a
statistically significant effect. Biomarker data failed to clarify patterns in
pregnancy outcome data. Results concerning the impact of the intake of omega-
3 fatty acids on the development of infants are primarily, although not uniformly,
inconclusive. The inconsistencies in study results may be attributable to
numerous factors. Reliably ascribing definite child outcome-related benefits, or
the absence thereof, to specific omega-3 fatty acids is difficult. Biomarker data
failed to clarify patterns in child outcome data. Future research should likely
consider investigating the impact of specific omega-6/omega-3 fatty acid intake
ratios. To produce results that are applicable to the North American population,
populations consuming high omega-6/omega-3 fatty acid intake ratios should
likely be randomized into trials also exhibiting better control of confounding
variables than was observed.
The NIH State-of-the-Science Conference on the Role of Multivitamins/
Minerals (MVM) in Chronic Disease Prevention is in the planning stages and is
scheduled for May 15�17, 2006. The Program Committee for this Conference is
provided as Appendix C. The Conference Questions are:
(1) What are the current patterns and prevalence of the public's use of MVM?
(2) What is known about the dietary nutrient intake of MVM users versus non-
users?
(3) What is the efficacy of single vitamin/mineral supplement use in chronic
disease prevention?
(4) What is the efficacy of MVM in chronic disease prevention in the general
population of adults?

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(5) What is known about the safety of MVM for the generally healthy population?
(6) What are the major knowledge gaps and research opportunities regarding
MVM use?

POTENTIAL TRANS-NIH ACTIVITIES
Dr. John Milner, NCI, discussed the National Food and Nutrient Analysis
Program (NFNAP) which allows for the generation of nationally representative
analytical data for frequently consumed US foods for the USDA National Nutrient
Databank for Standard Reference (SR) and also for the development of
databases for additional food components of current research interest. The SR
and other food composition databases are available at
www.nal.usda.gov/fnic/foodcomp. The data in SR and the other databases are
widely used by NIH Institutes and Centers (ICs) as well as by other agencies in
DHHS (FDA, CDC, IHS). For many years, Dr. Abby Ershow, National Heath,
Lung, and Blood Institute (NHLBI), has coordinated the contribution of NIH and
other DHHS funds to NFNAP. Dr. Milner has now taken over this activity and
welcomes IC interest and contributions. Contact Dr. Milner for more information
about contributing to NFNAP.
Dr. Milner also introduced the topic of Biomarkers as an activity that should be
considered by the NCC members. He discussed the importance of biomarkers
with regard to NIH research and proposed that the NCC could (1) develop a
collaborative venture across agencies to identify and validate biomarkers for
exposure, effect, and susceptibility and (2) develop working groups to deal with
the "omics" of nutrition as related to health.

Action item: Please provide a name or a point of contact within your
organization to work with Dr. Milner and others on this initiative. Contact Dr.
Milner for more discussion and information about this topic.

Dr. Milner announced a presentation by Dr. Robert Weinberg from the
Whitehead Institute for Biomedical Research at the Massachusetts Institute of
Technology, Cambridge MA on Mechanisms Leading to the Formation of Human
Malignancies on September 28, 2005, 9-11 AM at the Lipsett Amphitheater,
Building 10, Main NIH Campus, Bethesda MD.
Also of interest to NCC members was the announcement of a workshop on
Frontiers in Metabolomics for Cancer Research on October 24-25 at the Double
Tree Hotel in Rockville MD. Additional information is available from Dr. Young
Kim, NCI at 301 496-0216 or kimyoung@mail.nih.gov.

UPDATE FROM THE DHHS OFFICE OF DISEASE PREVENTION AND
HEALTH PROMOTION (ODPHP)
Ms. Kathryn McMurry, ODPHP, provided an update of the Dietary Reference
Intake Subcommittee activities. As mentioned at the last NCC Meeting, the DRI
Federal Steering Committee has been exploring several aspects of the DRI
process. The agencies represented on this Steering Committee include several
from Health Canada, DHHS, USDA, and DoD. The Committee is pursuing a

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request for a new task order for the Institute of Medicine (IOM) to prepare a
synthesis of the research recommendations from the individual DRI reports with
partial funding from ODS, DNRC, and ODPHP. Additional funds are expected
from USDA and Health Canada. This will become part of a larger process to
identify where gaps exist, assess federal activities, and consider research
priorities. Ongoing discussions have been held to explore various approaches to
assessing lessons learned from the current DRI process and ways to enhance
future evaluations. It is important to do this before embarking on any new
studies. A small group has met with the leadership of IOM to explore options for
working collaboratively on these assessments. This will be discussed in further
detail with the Steering Committee at a meeting at the end of September 2005.
Ms. Chris Dobday, ODPHP, and Ms. Kim Stitzel, ODPHP, discussed the
DHHS book, A Healthier You: Based on the Dietary Guidelines for Americans.
The purpose of the book is to get the Dietary Guidelines for Americans (DGAs) to
consumers. The book is consumer friendly and maintains the integrity of the
DGAs. It is based on information from focus groups and is written in plain
language. It contains over 100 heart healthy recipes as well as the DGAs. A
quick DHHS/USDA review of the book is requested to allow for copies to be
distributed at the October 24-25, 2005 3rd National Prevention Summit:
Innovations in Community Prevention
(http://www.healthierus.gov/steps/summit.html). The book will be available in
local bookstores and may be downloaded from the web at no cost. Copies for
federal employees with the print rider are $3.50. Five copies of the draft book
were sent to the DNRC for review and were given to Dr. Darla Danford (NHLBI),
Dr. Sue Krebs-Smith (NCI), Dr. Carolyn Miles National Institute for Diabetes and
Digestive and Kidney Diseases (NIDDK), Dr. Yetley (ODS)/Ms. Martina Vogel-
Taylor (NIH OD), and Dr. Jean Pennington (DNRC). Comments are due to Dr.
Pennington by noon on September 8, 2005. The comments will be collated at
the DNRC and forwarded to ODPHP on September 12, 2005.

UPDATE OF DNRC ACTIVITIES
Nutrition Education Subcommittee (NES). Dr. Jean Pennington, DNRC, provided
an update of the activities of the NIH NCC NES. Since the beginning of 2005, 42
items have come in for review including 18 from NIH (five from NCI, one from the
DNRC, two from the National Institute for Child Health and Development
(NICHD), three from NHLBI, two from ODS, two from the Weight-control
Information Network (WIN), and three from NIDDK; nine from DHHS; 14 from
USDA; and one from the Department of Defense (DoD). Materials reviewed
since the last NCC meeting include:
- Choosing Food for a Day (Food and Nutrition Service (FNS), USDA)
- Three Spotlights (National Agriculture Library (NAL), USDA)
- Consumer Gameplan Toolkit (NIDDK)
- Fact Sheet on Carnitine (ODS)
- Fact Sheets for Older Adults (Administration on Aging (AoA))
- Fact Sheets on Nutrition Facts and Trans Fat (FDA)
- Through the Eyes of the Eagle (2 children's books) (CDC)

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- Keep the Beat Heart Health Calendar (NHLBI)
- Power Plan: Snack Smart; Choose Drinks that Count (FNS, USDA)
- A Healthier You: Based on the dietary guidelines for Americans (ODPHP)

International Committee
Dr. Daniel Raiten, NICHD, noted that there would be an NIH workshop on The
Role of NIH in International Research at the International Nutrition Congress in
Durbin, South Africa in September 2005. Attending this workshop from NIH will
be Dr. Sooja Kim, CSR; Dr. John Milner, NCI; Dr. Pam Starke-Reed, DNRC; and
Dr. Raiten. The focus for the workshop will be outsiders looking in (at NIH) and
insiders looking out. Contact Dr. Raiten for more information.

Human Nutrition Research and Information Management (HNRIM) System
Update. Mr. Jim Krebs-Smith, DNRC, provided a status report of the HNRIM
System. The Fiscal Year (FY) 2004 report of NIH nutrition research and training
has been completed and is available on the public HNRIM website
(http://hnrim.nih.gov). Powerpoint slides of tables from this report will also be
available within the next few days. Mr. Krebs-Smith also reported that
modifications of the HNRIM public and restricted-access websites are underway.
These changes will provide users with more options for generating, viewing, and
printing reports and will link records to related PubMed publications. Completion
of these enhancements is expected by the end of September 2005.

DHHS Obesity-Related Activities
Dr. Hubbard noted that the Committee on Science of the Office of Science and
Technology Policy (OSTP) (Executive Office of the President) would convene a
conference in early in 2006 to focus on obesity. An OSTP planning meeting is
scheduled for September 22, 2005. Dr. Elias Zerhouni has been asked to lead
the organization of this conference, which is to involve agency heads from all
federal agencies.
Dr. Hubbard also noted that he will be serving a part-time detail to DHHS to
be the Chair of a DHHS workgroup to coordinate efforts on obesity. He will be
involved in the OSTP planning and will communicate through the NCC on these
activities.

REPORTS FROM NCC MEMBERS AND LIAISIONS
Dr. Sue Krebs-Smith, NCI, mentioned a grant from the University of Arizona for
the International Dietary Assessment Methods Conference which is to be held in
Denmark on April 27-29, 2006. NCI will provide partial support for this grant; Dr.
Krebs-Smith invites other interested NIH co-sponsors to contact her.

Dr. Mary Frances Picciano, ODS, announced the following seminars from the
ODS Fall Seminar Series:
- Josh Berman, MD, Director, Office of Clinical and Regulatory Affairs (OCRA),
NCCAM. "Botanical Drugs as of 2005: the view from OCRA." September 21,
2005 at 11:00 AM in room 2B03, 6100 Executive Boulevard, Rockville MD.

6
- Leann L Birch, PhD, Distinguished Professor of Human Development, The
Pennsylvania State University. "Psychosocial Determinants of Childhood
Obesity." October 5, 2005 at 11:00 AM. Location TBA.
Dr. Picciano also announced that the ODS Trans-NIH/Agency Working Group
will meet October 27, 2005 at the Neurosciences Center, 6001 Executive
Boulevard, Rockville MD from1:30-3:00 PM. An agenda will be provided later
this month.

NEXT NCC MEETING
The next NCC Meeting is scheduled for October 6, 2005.

ADJOURNMENT
Dr. Hubbard asked for a motion to adjourn the meeting, and a motion was so
made by Dr. Milner, NCI. The meeting was adjourned at 4:10 PM.

LIST OF APPENDICES
Appendix A - NIH NCC Meeting Agenda for September 1, 2005
Appendix B - NCC Meeting Attendees for September 1, 2005
Appendix C - Planning Committee for the NIH State-of-the-Science Conference
on the Role of Multivitamin/Mineral Supplements in Chronic
Disease Prevention

4Oct2005draftjp

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APPENDIX A. NIH NCC MEETING AGENDA FOR SEPTEMBER 1, 2005
2:00-4:00 PM, Rockledge 2, Conference Room 9112-9116, Bethesda MD

1. Welcome........................................................................Van Hubbard
2. Approval of Minutes of the July 7, 2005 Meeting..................Van Hubbard
3. Scientific Presentation:
"A Comparison of Three Food Guides: the USDA Food Guide, DASH
Eating Plan, and Willett's Healthy Eating Pyramid" by Dr. Jill Reedy,
Cancer Prevention Fellow, National Cancer Institute
4. Update from the Office of Dietary Supplements....................Beth Yetley
5. Update from ODPHP..................................................Kathryn McMurry
DHHS A Healthier You: Based on the Dietary Guidelines for Americans
Dietary Reference Intake Subcommittee
6. Potential Trans-NIH Activities.............................................John Milner
National Food and Nutrient Analysis Program
Biomarkers of Disease Risk
7. DNRC Activities Update
Nutrition Education Subcommittee................. ...............Jean Pennington
International Committee............................Pam Starke-Reed/Dan Raiten
HNRIM ...................................................................Jim Krebs-Smith
DHHS Obesity-Related Activities......................................Van Hubbard
8. Reports from NCC Members and Liaisons.......................NCC Members
9. Next Meeting: October 6, 2005..........................................Van Hubbard
10. Adjournment..................................................................Van Hubbard

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APPENDIX B. NCC MEETING ATTENDEES FOR SEPTEMBER 1, 2005
Members Present Members Absent Alternates Present
Chairperson: V Hubbard P Starke-Reed

NIH Members:
NCI J Milner
NHLBI D Danford
NIDCR R Nowjack-Rayner
NIDDK C Miles
NINDS M Mitler R Desrocher
NIAID M Plaut
NIGMS S Somers
NICHD G Grave D Raiten
NEI N Kurinij
NIEHS E Maull
NIA J Finkelstein
NIAMS J McGowan
NIDCD B Wong
NIMH P Muehrer
NIDA G Lin
NIAAA V Purohit R Breslow
NINR Y Bryan
NCCAM M Klein
NCRR L Yager
FIC N Tomitch
NCHGR K DeLeon

NIH Liaison Members:
CC N Sebring
CIT J Mahaffey
CSR S Kim
NLM S Phillips
OBSSR D Olster
OC M Stern
ODS P Coates
OD/ODP B Portnoy
OLPA
ORWH
PRCC M Vogel-Taylor

Agency Liaison Representatives:
CDC/NCCDPHP D Galuska
CDC/NCHS V Burt
FDA K Ellwood
HRSA M Lawler
IHS T Brown J Charles-Azure
ODPHP K McMurry
USDA M Kretsch
DoD K Friedl

DNRC: W Johnson-Taylor, C McDade-Ngutter, J Pennington, K Regan, L Somuah

Guests: S Adamo (HRSA), G Bathalon (DoD), C Davis (NCI), J De Jesus (NHLBI), C Dobday
(ODPHP), A Ershow (NHLBI), J Holden (ARS, USDA), A Jerkins (CSR), E Obarzanek (NHLBI),
MF Picciano (ODS), J Reedy (NCI), S Ross (NCI), J Seymour (CDC), K Stitzel (ODPHP), R
Troiano (NCI), Susan Welsh (CSREES, USDA), S Yanovski (NIDDK), B Yetley (ODS)

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APPENDIX C. Planning Committee for the NIH State-of-the-Science
Conference on the Role of Multivitamin/Mineral Supplements in Chronic
Disease Prevention

Planning Chairs: Paul M. Coates, Ph.D.
Director
Office of Dietary Supplements
Office of the Director
National Institutes of Health
Building 17, Room 3B01
6100 Executive Boulevard, MSC 7517
Bethesda, MD 20892-7517
Phone: 301�435�2920
Fax: 301�480�1845
E-mail: pc61s@nih.gov

Johanna Dwyer, D.Sc., R.D.
Senior Nutrition Scientist
Office of Dietary Supplements
Office of the Director
National Institutes of Health
6100 Executive Boulevard, Room 3B01
Bethesda, MD 20892
Phone: 301�435�2920
Fax: 301�435�2920
E-mail: jd426g@nih.gov

Meir Stampfer, M.D., Ph.D. Mayada Akil, M.D.
Professor of Nutrition and Epidemiology Office of Science Policy and Program
Chair, Department of Epidemiology Planning
Departments of Epidemiology and National Institute of Mental Health
Nutrition National Institutes of Health
Department of Epidemiology Neuroscience Building, Room 8203
Kresge Building, 9th Floor 6001 Executive Boulevard
677 Huntington Avenue Bethesda, MD 20892-9637
Boston, MA 02115 Phone: 301�443�4335
Phone: 617�432�6477 E-mail: makil@mail.nih.gov
Fax: 617�566�7805
E-mail: mstampfe@hsph.harvard.edu

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David Atkins, M.D., M.P.H. Gerald Combs, Jr., Ph.D.
Chief Medical Officer Center Director
Center for Practice and Technology Grand Forks Human Nutrition Research
Assessment Center
Agency for Healthcare Research U.S. Department of Agriculture
and Quality 2420 Second Avenue, North
540 Gaither Road, Sixth Floor Grand Forks, ND 58202-9034
Rockville, MD 20850 Phone: 701�795�8456
Phone: 301�427�1608 Fax: 701�795�8230
Fax: 301�427�1639 E-mail: gcombs@gfhnrc.ars.usda.gov
E-mail: datkins@ahrq.gov
Margaret Coopey, R.N., M.G.A., M.P.S.
Barbara A. Bowman Health Policy Analyst
Associate Director for Policy Studies Center for Practice and Technology
National Center for Chronic Disease Assessment
Prevention and Health Promotion Agency for Healthcare Research
Chronic Disease Prevention and Quality
Centers for Disease Control and U.S. Department of Health and
Prevention Human Services
1600 Clifton Road 540 Gaither Road
Atlanta, GA 30333 Rockville, MD 20850
Phone: 770�488�6011 Phone: 301�594�4022
Fax: 770�488�5966 Fax: 301� 594�4027
E-mail: barbara.bowman@cdc.hhs.gov E-mail: mcoopey@ahrq.gov

Elsa A. Bray Cindy D. Davis, Ph.D.
Senior Advisor for the Consensus Nutritional Science Research Group
Development Program (HNC4D)
Office of Medical Applications of Research National Cancer Institute
Office of the Director National Institutes of Health
National Institutes of Health 6100 Executive Boulevard, Suite 3159
6100 Executive Boulevard, Room 2B03 Bethesda, MD 20892-7328
Bethesda, MD 20892 Phone: 301�594�9692
Phone: 301�496�4999 Fax: 301�480�3925
Fax: 301�402�0420 E-mail: davisci@mail.nih.gov
E-mail: braye@od.nih.gov
James Everhart, M.D., M.P.H.
Emily Chew, M.D. Chief
Deputy Director Epidemiology and Clinical Trials Branch
Division of Epidemiology and Division of Digestive Diseases and Nutrition
Clinical Research National Institute of Diabetes and Digestive
National Eye Institute and Kidney Diseases
National Institutes of Health National Institutes of Health
Building 10, Room 3-2531 Two Democracy Plaza, Room 655
10 Center Drive MSC 1204 6707 Democracy Boulevard, MSC 5450
Bethesda, MD 20892-1204 Bethesda, MD 20892-5450
Phone: 301�496�6583 Phone: 301�594�8878
Fax: 301�496�2297 Fax: 301�480�8300
E-mail: echew@nei.nih.gov E-mail: je17g@nih.gov

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Judith A. Finkelstein, Ph.D. Barnett S. Kramer, M.D., M.P.H.
Health Scientist Administrator Director
Neuroscience and Neuropsychology of Office of Medical Applications of Research
Aging Program Office of the Director
National Institute on Aging National Institutes of Health
National Institutes of Health 6100 Executive Boulevard, Room 2B03
Gateway Building, Suite 3C307 Bethesda, MD 20892
7201 Wisconsin Avenue Phone: 301�496�1508
Bethesda, MD 20892-9205 Fax: 301�480�7660
Phone: 301�496�9350 E-mail: bk76p@nih.gov
Fax: 301�496�1494
E-mail: jf119k@nih.gov Molly Kretsch, Ph.D.
National Program Leader for Human
Gilman D. Grave, M.D. Nutrition ARS, USDA
Chief 5601 Sunnyside Avenue, GWCC 4-2192
Endocrinology, Nutrition, and Beltsville, MD 20705-5138
Growth Branch Phone: 301�504�5138
National Institute of Child Health E-mail: Molly.Kretsch@nps.ars.usda.gov
and Human Development
National Institutes of Health Catherine Loria, Ph.D.
Building 17, Room 4B11 Epidemiologist
6100 Executive Boulevard National Heart, Lung, and Blood Institute
Bethesda, MD 20892 National Institutes of Health
Phone: 301�496�5593 Rockledge Center II, Room 8112
Fax: 301�480�9791 6701 Rockledge Drive
E-mail: gg37v@nih.gov Bethesda, MD 20892
Phone: 301�435�0702
Laura Kettel Khan, Ph.D. Fax: 301�480�1667
Deputy Chief E-mail: loriac@nhlbi.nih.gov
Chronic Disease Nutrition
Division of Nutrition & Physical Activity Kelli K. Marciel, M.A.
Centers for Disease Control and Prevention Communications Director
4770 Buford Highway, MS K26 Office of Medical Applications of Research
Atlanta, GA 30341 Office of the Director
Phone: 770�488�6018 National Institutes of Health
Fax: 770�488�6027 6100 Executive Boulevard, Room 2B03
E-mail: ldk7@cdc.gov Bethesda, MD 20892
Phone: 301�496�4819
Marguerite A. Klein Fax: 301�402�0420
National Center for Complementary and E-mail: marcielk@od.nih.gov
Alternative Medicine
National Institutes of Health J. Michael McGinnis, M.D., M.P.P.
6707 Democracy Boulevard, Suite 401 Counselor to the President
Bethesda, MD 20892 The Robert Wood Johnson Foundation
Phone: 301�402�5860 1100 Connecticut Avenue, N.W.
Fax: 301�480�3621 Washington, DC 20036
E-mail: kleinm@mail.nih.gov Phone: 202�293�4296
E-mail: mcginnis@rwjf.org

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Joan A. McGowan, Ph.D. Lester Packer, Ph.D.
Chief Professor
Musculoskeletal Diseases Branch Adjunct Faculty
National Institute of Arthritis and Department of Molecular Pharmacology
Musculoskeletal and Skin Diseases and Toxicology
National Institutes of Health University of Southern California School of
Building 45, Room 5AS-43E Pharmacy
45 Center Drive, MSC 6500 1985 Zonal Avenue
Bethesda, MD 20892-6500 Los Angeles, CA 90089-9121
Phone: 301�594�5055 Phone: 323�442�3355
Fax: 301�480�4353 Fax: 323�224�7473
E-mail: joan_mcgowan@nih.gov E-mail: packer@usc.edu

Linda D. Meyers, Ph.D. Irwin H. Rosenberg, Ph.D.
Director Senior Scientist and University Professor
Food and Nutrition Board Jean Mayer U.S. Department of Agriculture
Institute of Medicine Human Nutrition Research Center
The National Academies Tufts University
500 Fifth Street, N.W. 711 Washington Street
Washington, DC 20001 Boston, MA 02111-3794
Phone: 202�334�3153 Phone: 617�636�3701
Fax: 202�334�2316 Fax: 617�636�3794
E-mail: lmeyers@nas.edu E-mail: irwin.rosenberg@tufts.edu

Lata S. Nerurkar, Ph.D. Susan Rossi, Ph.D., M.P.H.
Senior Advisor for the Consensus Deputy Director
Development Program Office of Medical Applications of Research
Office of Medical Applications of Research Office of the Director
Office of the Director National Institutes of Health
National Institutes of Health 6100 Executive Boulevard, Room 2B03
6100 Executive Boulevard, Room 2B03 Bethesda, MD 20892
Bethesda, MD 20892 Phone: 301�496�5641
Phone: 301�435�5060 Fax: 301�402�0420
Fax: 301�402�0420 E-mail: rossis@od.nih.gov
E-mail: nerurkal@od.nih.gov
John Paul SanGiovanni, Sc.D.
Malden C. Nesheim, Ph.D. Staff Scientist
Professor of Nutritional Sciences Division of Epidemiology and Clinical
Emeritus Research
Provost Emeritus National Eye Institute
Division of Nutritional Sciences National Institutes of Health
College of Human Ecology Building 10, Hatfield Clinical Research
Cornell University Center Room 3-2531
311 Savage Hall 10 Center Drive MSC 1204
Ithaca, NY 14853 Bethesda, MD 20892-1204
Phone: 607�255�4058 Phone: 301�496�6583
Fax: 607�255�1033 Fax: 301�496�2297
E-mail: mcn2@cornell.edu E-mail: jpsangio@nei.nih.gov

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Paul A. Sheehy Amy F. Subar, Ph.D., M.P.H., R.D.
National Institute of Neurological Disorders Research Nutritionist
and Stroke National Cancer Institute
National Institutes of Health National Institutes of Health
Neuroscience Center, Room 2214A 6130 Executive Boulevard, MSC 7344
6001 Executive Boulevard Rockville, MD 20892-7344
Rockville, MD 20892 Phone: 301�594�0831
Phone: 301�496�5329 Fax: 301�435�3710
Fax: 301�480�1080 E-mail: subara@mail.nih.gov
E-mail: sheehyp@ninds.nih.gov
Anne Thurn, Ph.D.
Pamela Starke-Reed, Ph.D. Director
Deputy Director Evidence-Based Review Program
Division of Nutrition Research Coordination Office of Dietary Supplements
National Institute of Diabetes and Digestive National Institutes of Health
and Kidney Disease 6100 Executive Boulevard, Room 3B01
National Institutes of Health MSC 7517
Room 679 Bethesda, MD 20892-1845
6707 Democracy Boulevard, MSC 5461 Phone: 301�435�2920
Bethesda, MD 20892-5450 E-mail: thurna@mail.nih.gov
Phone: 301�594�8805
Fax: 301�480�3768 Paula R. Trumbo, Ph.D.
E-mail: pamela.starke-reed@nih.hhs.gov Division of Nutrition Programs and
Labeling
U.S. Food and Drug Administration
HFS-830
5100 Paint Branch Parkway
College Park, MD 20740
Phone: 301�436�2579
Fax: 301�436-2636
E-mail: paula.trumbo@fda.hhs.gov